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ADHS

Poster

ADHD, trauma and attachment - A new etiological model

Vuksanovic N, Brisch K H
Department Pediatric Psychosomatic Medicine and Psychotherapy

Introduction: ADHD is described as a multifactorial disease. Genetic factors as well as early environmental factors such as prenatal exposure to nicotine/alcohol but also quality of parental care giving and early deprivation play an important role in the development and course of the disorder. In recent etiological studies gene x environment (GxE) interactions are considered as probable mechanism by which those early-development environmental insults can lead to long term alterations in phenotype.
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Boys with ADHD and their mothers: what can we learn from the neuroendocrinology?

Vuksanovic N.*, Kern C.*, Zeber K.*, Bidlingmaier M.**, Borns J.*, Brisch K .H.*
Objective: We know from the previous research that the stress response in healthy children , especially to emotional and attachment specific stressors, depends on attachment quality of the child, which is highly predicted by the attachment representation of the mother. Since children with ADHD seem to show different stress reaction patterns and deficient emotional self-control, the aim of our study was to investigate the factors influenced by the attachment figure, mostly mother, and the impact of the attachment quality of the child on neuroendocrinologic regulation in boys with ADHD.
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The Importance of HPA Axis as an Etiological Factor in Boys with ADHD

Vuksanovic N.*, Bidlingmaier M.**, Zeber K.*, Borns J.*, Kern C.*, Brisch K .H.*
Objective: Through the experimental research utilizing animal models, we better understand how early life stress induces alterations in epigenetic programming, subsequent HPA stress response and development of aggressiveness / hyperactive behavior (1). Additionally, a few specific genetic factors seem to play an important role in this process. Some evidence suggests that the HPA axis may be dysfunctional in children with ADHD (2) and may be an important etiological factor. The objective of our cross-sectional study was to compare basal cortisol levels as well as stress reaction patterns to a cognitive stressor in children with ADHD and healthy controls.
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Adrenocortical functioning in boys with attention-deficit/hyperactivity disorder (ADHD)


Vuksanovic N, Kern C, Göttler C, Zeber K, Brisch K H
Introduction: Through the experimental research utilizing animal models, we better understand how early life stress (trauma, neglect, poor maternal care) induces alterations in epigenetic programming, subsequent HPA stress response and development of aggressiveness / hyperactive behavior (1). Some evidence suggests that the HPA axis may also be dysfunctional in children with ADHD (2) and may be an important etiological factor.
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Sind Jungen mit ADHS doch sensibler in ihrer Stressreaktionsbereitschaft?


Vuksanovic, N.*; Zeber, K.*; Kern, C.*; Bidlingmeier, M.; Brisch, K.H.*;

Einführung:
Die HPA-Achse entwickelt sich bei Menschen in den ersten Lebensjahren und reagiert hoch sensibel auf frühe Erfahrungen von Deprivation und Misshandlung. Anhand von Tiermodellen können wir besser verstehen, wie frühe Trennungserfahrungen und mangelnde emotionale Verfügbarkeit der Mutter durch epigenetische Programmierung einerseits zu depressiven / überängstlichen und andererseits zu hyperaktiven / aggressiven Zeichen auf der Verhaltensebene führen. (Kapoor, 2006; Weaver, 2009; Mcgowan, 2009; Veenema, 2009).
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Wissenschaftliche Publikationen zu ADHS:

ADHS Diagnostik und Hilfen für betroffene Kinder und Jugendliche und ihre Eltern

Gesamtes Werk (6 MB): download

Karl Heinz Brisch: Posttraumatische Belastungsstörung und Störungen der Aufmerksamkeit
                             und Hyperaktivität
,  auf Seite 35

Herausgeber: Bundesarbeitsgemeinschaft der Kinderschutz-Zentren e.V., zur Website: hier

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